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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'd72bbfb3016d5dcc4f47da2db8a7a02350fa255e59cc674d00536744c3de2eeb' 
  AND token = 'xzjD2/L/QRZAIOkomeFCDpUnORyQC7qAF+yC5UQsmk0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}