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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '0c5193f0bc163b1b856a07072c0bead7cbffacad5286ab3afee5d3cd80c52b05' 
  AND token = 'Frn3yPrAcJlcXaxr0w5F9vGFZYWopVsrhN3xPkMrKg0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}