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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '6b60a114f8c9b6b6c625d4d45ba25019ede5e66605b7e0be348884b967be24f0' 
  AND token = 'Pp2e0CLkjh0ErSRKLREZvdZnPpRsYzoMIFwDmjXTsao=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}