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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '8fd8fd7b4f9b81644aee2d6824050d46e1df3d1e6481ecd92e046ee5ea4980aa' 
  AND token = 'CgeIoePm2yq36N3+9JWW9GsflwKyozSgLjOqA6ARrtw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}