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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '7acbc4ce280d2e7b6587659f347769aedf8c55a1411a13aaf165cff7562182af' 
  AND token = 'GsSCL0e76f/gnr8wFGevD8atueZ7UcR3ZYyjZ1IQt/8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}