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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '94279678c98e6ea7156cf1f6373342f7699dc9aec1ab339dcffb6a6374929d5c' 
  AND token = 'IRXX5xlzyVnEwWY8/WiI6qMCuEPyI+0WXV1nyuxGmr4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}