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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '8a42922b70eb0e0d210600b522a8bbfff2f3796c51234253d037c76b54ff67dd' 
  AND token = 'wqdxKoL9C84rLJ8mfCfyO2npcyoQ5aT2huP4LAgFczg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}