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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'be3f299c8e595b076c1a7b7cec8b735d21011e29b6a7f596541a2aca90611780' 
  AND token = '7LjEQOaRzPNsD6TbdRXsmJV4fEdhvlTTWIMOrS1kzEU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}