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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'b18e82530d809a1d18f8ab391f3002902531401437774740c7214b806b5855b0' 
  AND token = 'bspA1YQXoSy9UdxjTGieaP8duHqcnOABImqC72CeFbQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}