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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'ae2f78731eedd68923e7ac61f18f399a8c6d800123710c72258702c5b8261022' 
  AND token = '+djbQAtoDHzVkS0HmjVrPuSeWQ1XE2bRFHB4wxHPjrE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}