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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'd967f1218203c66291f07be66f5f870ae49af5b0b1b067f053064b42b8cf1c25' 
  AND token = 'NJotXynKxcfgGE10c8MHbZkyfArvEnWxGYysz5v8uXM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}