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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '4b01ebf831faff2cf14f08a2f521dbfc650e7734dd2b4b9de965efd1c69c790a' 
  AND token = 'JUoxpdO0nzAfD2y+jz9AppQm7DaRJQOGmYLF8P+sNDc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}