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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '01094559b08c2521667cef913e80a0d4cb233b53fb2ec580794b027de6b02520' 
  AND token = 'PcYeLMx/1DeRD4q6hJx2Wwx2QqDQ8kKw5KqRWvjS42c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}