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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'ec4e0f5654b2b43fb7a6f17a10fad083d399cc8954a97ef322dabceded7e8281' 
  AND token = 'jeNEwNBcSNj9QfcI1hF04TSostmMTNxo9gRKVv+1t9M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}