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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '4228fd8d0d4914ce6e22ce8faa17d80c9333bffe9ebb3215122fd5434e87315b' 
  AND token = 'lSY4Cozz/y3k2Kl752it9lKA7nRL/WRx5NlTXjCJ68w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}