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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '81725149aedb4aedb9133e8090384feeba3fba278926f8705643b2c681a33f25' 
  AND token = 'NX0J73bvSUWerb1THtnt1rdZqJptL5pG8OXnMqCPZUM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}