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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'f2a0b51f09692fcab114f1a66eaee643d41abef1fde977b8cf09f6484f6fa0db' 
  AND token = 'p9TUbBpsnLouvxL9v8/1IADLKVb7h/zDA4FcCtsb3sI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}