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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'b7b5f34875bc629e4af07cfad0e26b998ea8555e26a3b8dead71aa6b43e506c0' 
  AND token = 'QhONQIB3ePLlzBuCQ5bFIA/9lNYQ6XKJzuCIbA8XuL8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}