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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '648c78fa1d705c017cbba6b7a9189daf53a2e39455c8ae5f47349407d2f1b1bf' 
  AND token = 'jM4XXcm2cfRJcUi5B2mvIoMDq5G79O/7mUpHYUD4Ea8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}