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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'f59af239e3f3315f9af5fc694d1980aae33abd2038e2a530a5ecbb4ed485c462' 
  AND token = 'cRh4WXshEAWKKDbda3UgAszFxgIR44JY0h3IXhbdKsI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}