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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '396e5670bc4b07010390451016a017c91a1ee82cea1974550031ea1e771c026b' 
  AND token = 'e0pg7AZTu2a8DWKXy1CqCmZtnwMhM/PC8A9nORW+65E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}