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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '69adff6581cab86333162881f7200b298eb3a60fef0ec9d47e34f3138169b250' 
  AND token = 'jCeE05kbnqXmTO1c3oKeWbIufyKPLC9KOkWIWAKmnM4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}