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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '4c9c5cd74953b7237c232b5a4e664fbf830feed2af9dc0321cb1c4c9c865de5b' 
  AND token = 'EpPD8iAd7YgS+znYu5jgK5wjNUI09jrdgSuN8UDhY9c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}