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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'acacc8178c37080c00924d53ea22f6a927865288f243b3027e77a346a878c0e5' 
  AND token = 'xY70603VV0URJZAD5s2ZswW3V+hWMlcelbohhY1gLOw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}