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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'fed50aa31612c81172b50dc15a1bbfcc9d3518be6cbcd78edf6a95927843e146' 
  AND token = 'p8y/kDCzyK5niUM7w6UF4uUFfBYcj08KuOKDcsTm4Tw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}