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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'e84f9f7a41ec7d03324924e3c694665e1cffb0b70fdb293049ffc24edfb4106c' 
  AND token = 'hMpzn7UOXQ8Rmmp3JBbhRhHAXuaFnYOzORa37TlSjGE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}