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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'cef8e413e1e7913c30f07d473754bf72d17d6456927f2d56c14ca2369e8e6be3' 
  AND token = 'D10ev/dfB8KVD3u6QbbMCtX9E01m17Dij45XHTT9WWE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}