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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'a8120328dcde536072c6819c0e6bf6a74686fdb22aed7b5f600df19ba6b6c165' 
  AND token = 'zIybqUc+fxSOWFgARWuko2UcsrzzyY3ibL5O3HavTso=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}