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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'bea49840255122153231042932cd362a828248bf0f0a3962a1ab7eb382009298' 
  AND token = 'K1ShzMbYzfwR71GOWP9sBxMkj9CMKzIBidtX3jt7b9g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}