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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '727e14f6c98811e8cb1f476a449ec8854a448043edf90dc76ff000ed613990c0' 
  AND token = 'AWP3fWVAE/lkT2c03lhJb06WYmWMUdsX5sEAd/e3C54=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}