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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '6d4218e72cab9bf99379c9e2e7b3777fa5127811f2582460d51eed26f2786e52' 
  AND token = 'wNFEO4UhUUhyWt2mu33HYHeUlQtSje9sbS0xSSbIqqI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}