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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '53acf59c09ada42c5bde468c6498079a7a2adf162384d3b651f90363d0dc683e' 
  AND token = '2pwaDdS8TmaxoOTzsVHbVKp/r5BjQt4CMOqNqKWSnuM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}