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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'e893f04e5c33dfb614138d31f50423c9447af4fc229f3fc4f5e0be989fd1433b' 
  AND token = 'NF25729v/sOYu94WA+R0EJ+rgKguhQdO+aVSmjinoEg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}