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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '75effbd4f79389370b3c7fa54c626a597496244ba061dcf46086520f1da6506b' 
  AND token = 'O4oKeV7k3NLfXYUqKvFdHNMfuWVP2fPXbO5HZhKyYkM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}