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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '275a2611ae7eddf5724ab300d75b593cb321499b160d98f0f561f56c50c01fb7' 
  AND token = 'obkw2zJoXwcSFcOoa/uXoFlg6Or7wWpEJ3bPKMMLpTs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}