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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'cd953d036315cf9f72fc5c3288ceb55398235574250631e2527150f87c2ad524' 
  AND token = 'kx2P0c1FZAsC4Zd3/bIlV/BKLeQVTXfPoDisuNSqw6w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}