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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '24aae1729aa92c6f5fa7195fd4b8cd421565b9ac60426e6b6ca517b6b204af97' 
  AND token = 'Sqb/YJm1YtstdisMNsyWcDcSsUXjyc48IfmioAy0E7c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}