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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '9fda8f46ed7b16dee9479c7f4a956838fecd324dfc89e18033ffc0c05fc89043' 
  AND token = '/Itf55nQ64D6cGt6Loqq0akVJqfbWiEuJ6Cnwa4+aGw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}