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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '5b10555d76bb224fa4629aff1d0535740fadb2bb9d2e0bbf4cf2ea0c59d7c2a7' 
  AND token = '16VV1yJMYsXLB0tHANT/Iux3y4viLanKncpRgoms40A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}