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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '364620f9818bc7b68564c6e08cbf1dc6f28e4adc17c862250104289faae1adc0' 
  AND token = 'OyIetktbeB3u78vY7n7+VvwcjaB8kDMdeh79bMCkj2Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}