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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'aaab20d6925f7c9e06bf4bac11082ca47ffe34aeb473f169ddbd28ed46ce7efd' 
  AND token = '2/kgheBjadT9wOc7X5Wp/YBGIulsAtXB0oRlhvr3wHA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}