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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '1bad3d50d316612c372c19cb5dff047d165ba61dfc49c43816222113a403486a' 
  AND token = 'ttapg/ZeEsuLfjeRtS6y8bIPnpAZz03ECxX3vQxb/yM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}