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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'ed1727921d0b177294aa9cbbd042bbe2b13bfd78b7249a1d9008df7d61b47e91' 
  AND token = 'J5bggKdGsOmeCXnvL4PS/QaCPwMs3/ldRDuVM6txjW8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}