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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '61c012235ef1a299aaba385d917541c5927034121459a3b1e476f0e201c40c28' 
  AND token = 'S392xRCUzthUuxdrY9JBcnQGYO5fjvNfCPOEUOWH4eM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}