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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '7166a4bb80837b040eff2f59fdaf6ab0ca5d7a0943e95c425e63a37b63e18ff6' 
  AND token = 'gS2/d6V8c7zNOdasegZVTZlXPK9lDweZzVMMbH/aA3U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}