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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '346e1d7c23ac73eeaff6c478264b4a4709605af531a1bf7da4961e799a9c8146' 
  AND token = 'uzyBAkS5d+Wv/OCPAFHT/x3AIaadqNEEFVDHzUFKlkk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}