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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '0b2db6f2914ab3f3b43add1b2dbabb83e4c7d43a5a237060da6b780a35a01c8f' 
  AND token = 'sK+dgHSbsaMi5NU6EAxkIhaLDQRiEHvznTGFB5I/NYg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}