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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'e570968dc4d78930fe143c843e2196fbea5e5cd8cdbf07a29d4cab9f785bc704' 
  AND token = 'X6b0OW6ghayGDW1XhL58W8aEimOFqIKb8gW6hkZ8OEQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}