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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '7a0f1014763af9b1158f5bd009e94934d397c3b1a35313e766f4a93de0072b2a' 
  AND token = 'noOBYk99NTG0iRUs3ftrRn6B5aSjcCAPqCKDc99xvKM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}