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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '160e36f704aa33e1dded6cb6da41dafb68da06e12547be397c83f396f0a3700c' 
  AND token = '7g6pfwCiI2dpQSbHScvnuKR3oWFAgd3NBmOYCrAnYCc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}